Natural apatite is four times more effective at repairing damage than the artificial apatite!
Although apatite can be synthesized artificially in a beaker, Professor Ito of Matsumoto Dental University investigated the difference between artificial apatite and natural apatite extracted from fish scales. As you can see in the picture below, when a hole was made in the skull of a rat and each apatite was embedded, natural apatite assimilated with the bone on both sides after two weeks and the hole was completely repaired, while the hole was not repaired with the artificial apatite even after eight weeks.
The “bone-bonding effect” of natural apatite
The reason for this is thought to be that natural apatite is not a tightly built structure, but rather an uneven crystal lattice of columns, which facilitates the movement of calcium ions, a component of bone. The trace metallic elements such as iron and zinc in the apatite further facilitate the movement of calcium ions. The "bone-bonding effect" is a special effect that can only be achieved with natural apatite.